Gastrin stimulates renal dopamine production by increasing the renal tubular uptake of l-DOPA
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چکیده
منابع مشابه
L-Dopa uptake and dopamine production in proximal tubular cells are regulated by b2-adrenergic receptors
Carranza, Andrea, Susana Nowicki, Marta Barontini, and Ines Armando. L-Dopa uptake and dopamine production in proximal tubular cells are regulated by b2adrenergic receptors. Am J Physiol Renal Physiol 279: F77–F83, 2000.—This study assessed the role of adrenergic receptors on the regulation of the uptake of L-dopa and the production of dopamine by renal tubular cells. Scatchard analysis showed ...
متن کاملL-Dopa uptake and dopamine production in proximal tubular cells are regulated by beta(2)-adrenergic receptors.
This study assessed the role of adrenergic receptors on the regulation of the uptake of L-dopa and the production of dopamine by renal tubular cells. Scatchard analysis showed two L-dopa uptake sites with different affinities (K(m) 0.316 vs 1.53 microM). L-Dopa uptake was decreased by the nonselective adrenergic agonists epinephrine or norepinephrine (40%), by the beta-selective agonist isoprot...
متن کاملSignaling cascade of insulin-induced stimulation of L-dopa uptake in renal proximal tubule cells.
The inward l-dihydroxyphenylalanine (L-dopa) transport supplies renal proximal tubule cells (PTCs) with the precursor for dopamine synthesis. We have previously described insulin-induced stimulation of L-dopa uptake into PTCs. In the present paper we examined insulin-related signaling pathways involved in the increase of l-dopa transport into isolated rat PTCs. Insulin (50-500 microU/ml) increa...
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A case of renal tubular acidosis (RTA) who had gradual onset of paralysis of lower extremities and persisted for a long time is presented. His primary workups were mistaken for muscular dystrophy. Eventually, an abdominal ultrasonography revealed small stones in both of the kidneys and his workup for the stones were in favor of distal renal tubular acidosis and advanced rickets with hypokal...
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The aim of this study was to demonstrate the effects of atrial natriuretic peptide (ANP) on organic cation transporters (OCTs) expression and activity, and its consequences on dopamine urinary levels, Na+, K+-ATPase activity and renal function. Male Sprague Dawley rats were infused with isotonic saline solution during 120 minutes and randomized in nine different groups: control, pargyline plus ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2017
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00116.2016